Cagrilintide (AM833) explained: an amylin analogue and how it is identified
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Cagrilintide is a synthetic long-acting analogue of amylin, developed under the code AM833. Amylin is also known as islet amyloid polypeptide (IAPP), so cagrilintide is classed as an amylin (IAPP) analogue. This guide covers its identifiers, how it differs from the incretin-class peptides it is often catalogued beside, and what to check in the documentation.
Cagrilintide at a glance
| Compound | Cagrilintide |
|---|---|
| Development code | AM833 |
| Synonyms | AM833, Cagrilintide Acetate |
| CAS number | 1415456-99-3 |
| Class | Amylin (IAPP) analogue |
| Supplied form | White lyophilised powder, 10mg per vial |
What is an amylin analogue?
An analogue is a synthetic compound built on the structure of a naturally occurring one, with deliberate changes to its sequence or side chains. Cagrilintide is built on amylin and is described in the literature as long-acting. It is studied in amylin receptor pharmacology.
How does Cagrilintide differ from incretin-class peptides?
The difference is the receptor family. Amylin analogues are studied at amylin receptors. Incretin-class peptides are studied at receptors such as GLP-1R and GIPR. These are distinct pathways, and the compounds are different molecules with different identifiers.
| Cagrilintide | Retatrutide | |
|---|---|---|
| Class | Amylin (IAPP) analogue | Multi-receptor agonist peptide |
| Receptor family studied | Amylin receptors | GIPR, GLP-1R and GCGR |
| CAS number | 1415456-99-3 | 2381089-83-2 |
The research literature frequently examines amylin and incretin analogues together, which is why the two classes are often listed side by side. See what is Retatrutide (LY3437943)? for the other compound in this table.
How is Cagrilintide supplied by Ascend Research?
| Listing | Format |
|---|---|
| Cagrilintide 10mg | One vial, single compound |
| [2V] Retatrutide + Cagrilintide Research Duo | Two separate vials, 10mg each, not premixed |
Both are dispatched from within Australia and grouped under peptide analogues.
What should the documentation show?
- The compound name and batch number match the vial label.
- An HPLC purity figure and an identity result.
- The salt form tested, where stated. Cagrilintide Acetate is a listed synonym.
- Appearance recorded as a white lyophilised powder.
Batch documents are on the COAs page. See also how to read a peptide certificate of analysis.
Frequently asked questions
What is Cagrilintide?
Cagrilintide is a synthetic long-acting analogue of amylin, also known as islet amyloid polypeptide (IAPP). It was developed under the code AM833.
What is the CAS number for Cagrilintide?
The CAS number for Cagrilintide is 1415456-99-3.
Is AM833 the same as Cagrilintide?
Yes. AM833 is the development code for Cagrilintide.
Is Cagrilintide the same class of compound as Retatrutide?
No. Cagrilintide is an amylin analogue studied at amylin receptors. Retatrutide is a multi-receptor agonist designed for GIPR, GLP-1R and GCGR.
Is the Retatrutide + Cagrilintide duo premixed?
No. The duo supplies two separate vials, one of each compound.
All Ascend Research products are sold strictly for laboratory research use only. They are not for human or animal use, and nothing in this article is medical advice.
The Ascend Research team
