Epitalon or Epithalon? Spelling, sequence and CAS number

Epitalon, Epithalon and Epithalone are three spellings of one compound: a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly. It is also written as the AEDG peptide, after the one-letter codes of its four amino acids. This guide covers the names, the identifiers, and how the compound differs from the similarly named epithalamin.

Epitalon at a glance

Compound Epitalon
Other spellings and names Epithalon, Epithalone, AEDG Peptide
CAS number 307297-39-8
Sequence Ala-Glu-Asp-Gly
Length 4 amino acids (tetrapeptide)
Supplied form White lyophilised powder, 10mg per vial

Why are there several spellings?

The name was transliterated into English in more than one way, so “Epitalon”, “Epithalon” and “Epithalone” all appear in the literature and on supplier listings. They refer to the same tetrapeptide. When names vary like this, the CAS number and the sequence are the reliable identifiers.

What does AEDG mean?

AEDG is the sequence written in one-letter amino acid codes: A for alanine, E for glutamic acid, D for aspartic acid and G for glycine. The order matters. A peptide with the same four amino acids in a different order would be a different compound.

How does Epitalon differ from epithalamin?

Epithalamin is a pineal extract, a mixture rather than a single defined molecule. Epitalon was developed as a short synthetic analogue of it: one defined tetrapeptide with a known sequence. The names are similar but they are not interchangeable, and Ascend Research supplies the synthetic tetrapeptide.

Which related short peptides are listed?

Epitalon sits alongside other short synthetic peptides in the catalogue. Each is a separate compound.

Listing Sequence or format
Epitalon 10mg Ala-Glu-Asp-Gly, one vial
Pinealon 20mg Glu-Asp-Arg, one vial
Cartalax 20mg Ala-Glu-Asp, one vial
[3V] Epitalon + Pinealon + Thymalin Research Set Three separate vials

These are grouped under short peptides and small molecules. Multi-vial formats are explained in peptide blends vs separate vials.

What should the documentation show?

  • The compound name and batch number match the vial label.
  • An HPLC purity figure.
  • An identity result consistent with the Ala-Glu-Asp-Gly tetrapeptide.
  • Appearance recorded as a white lyophilised powder.

Batch documents are on the COAs page. See also how to read a peptide certificate of analysis.

Frequently asked questions

Is Epitalon the same as Epithalon?

Yes. Epitalon, Epithalon and Epithalone are different spellings of the same synthetic tetrapeptide, Ala-Glu-Asp-Gly.

What is the CAS number for Epitalon?

The CAS number for Epitalon is 307297-39-8.

What is the sequence of Epitalon?

Ala-Glu-Asp-Gly, written AEDG in one-letter amino acid codes.

How many amino acids are in Epitalon?

Four. Epitalon is a tetrapeptide.

Is Epitalon the same as epithalamin?

No. Epithalamin is a pineal extract. Epitalon is a single defined synthetic tetrapeptide developed as a short analogue of it.

All Ascend Research products are sold strictly for laboratory research use only. They are not for human or animal use, and nothing in this article is medical advice.

The Ascend Research team

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Materials mentioned in this guide

For laboratory research use only. Not for human or animal use.