PNC-27 5mg — Research Grade
PNC-27 is a synthetic chimeric peptide combining an HDM-2 binding domain derived from p53 with a membrane-penetrating leader sequence. Ascend Research supplies it as a lyophilised white powder in 5mg vials at ≥99% purity, dispatched from within Australia for laboratory research use only.
Specifications
| CAS Number | 1159861-00-3 |
| Synonyms | PNC-27 Peptide, HDM-2 Binding Peptide |
| Structure | p53-derived domain + membrane-penetrating leader |
| Research Target | HDM-2 (human MDM2) |
| Purity | ≥99% by RP-HPLC |
| Appearance | White lyophilised powder |
| Available Strength | 5mg per vial |
| Solubility | Sterile water |
| Storage | 2–8°C, dry |
Research Context
PNC-27 appears in in vitro cell biology literature concerning the p53–HDM-2 interaction and membrane-active peptide design. It is a chimeric construct rather than a naturally occurring sequence. Ascend Research supplies PNC-27 strictly as a laboratory reference material; no representation is made regarding any physiological outcome, and it is not supplied for use in humans or animals.
Handling and Reconstitution
Allow the vial to reach room temperature before opening. Reconstitute with sterile water and swirl gently. Store the lyophilised powder dry at 2–8°C, refrigerate reconstituted material and use within 30 days. Avoid repeated freeze–thaw cycles.
What's Included
- One lyophilised vial (5mg)
- Protective packaging
Frequently Asked Questions
What is PNC-27?
A chimeric synthetic peptide pairing a p53-derived HDM-2 binding domain with a membrane-penetrating leader sequence.
What does HDM-2 stand for?
Human double minute 2, the human homologue of MDM2.
Is PNC-27 a naturally occurring peptide?
No — it is an engineered construct combining two distinct sequence elements.
What is PNC-27 reconstituted with?
Sterile water in most laboratory protocols.
How is PNC-27 stored?
Dry at 2–8°C. Refrigerate after reconstitution and use within 30 days.
Where does Ascend Research ship from?
Orders are dispatched from within Australia.
Important Notice
Supplied for laboratory research use only. Not for human or veterinary use, self-administration, clinical, diagnostic, or therapeutic application. This product is not a cosmetic, drug, or food product. The purchaser is responsible for compliance with all applicable regulations. By purchasing, you confirm that you are a qualified researcher or are acting on behalf of a research institution.
Supplied for laboratory research purposes only. Not approved for human or veterinary use, self-administration, or therapeutic application. Handle in accordance with applicable research regulations.