CJC-1295 No DAC and Modified GRF (1-29): one compound, two names
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CJC-1295 without DAC and Modified GRF (1-29) are two names for the same compound: a 29-amino-acid analogue of growth hormone releasing hormone (GHRH). The name “CJC-1295” on its own is ambiguous, because it is also used for a second form that carries an added component called DAC. This guide explains the difference and how to confirm which form a listing supplies.
CJC-1295 (No DAC) at a glance
| Compound | CJC-1295 without DAC |
|---|---|
| Synonyms | Modified GRF (1-29), Mod GRF 1-29, CJC-1295 without DAC |
| CAS number | 863288-34-0 |
| Length | 29 amino acids |
| Class | GHRH analogue |
| Supplied form | White lyophilised powder, 10mg per vial |
What does DAC mean?
DAC stands for drug affinity complex. It is a linker added to the peptide that is designed for albumin binding. CJC-1295 appears in the literature in two forms: with DAC, which includes that linker, and without DAC, which does not.
| CJC-1295 without DAC | CJC-1295 with DAC | |
|---|---|---|
| Also called | Modified GRF (1-29) | CJC-1295 DAC |
| DAC linker | Not present | Present |
| Supplied by Ascend Research | Yes | No |
The two forms are different molecules with different masses. A listing or a certificate of analysis should state which one it refers to.
How does it relate to GRF (1-29)?
GRF (1-29) is the first 29 amino acids of GHRH, listed separately as Sermorelin. The no-DAC form of CJC-1295 carries four amino acid substitutions relative to that native sequence, which is why it is called Modified GRF (1-29). For a side-by-side view of the GHRH analogues, see Tesamorelin vs Sermorelin.
Which listings contain CJC-1295 (No DAC)?
| Listing | Format |
|---|---|
| CJC-1295 (No DAC) 10mg | One vial, single compound |
| [1V] CJC-1295 + Ipamorelin Blend 10mg | One premixed vial: CJC-1295 (No DAC) 5mg and Ipamorelin 5mg |
| [2V] CJC-1295 No DAC + Ipamorelin Research Duo | Two separate vials, 10mg each |
Ipamorelin is a different compound from a different class. See the Ipamorelin guide, and peptide blends vs separate vials for how the blend and duo formats differ.
What should the documentation show?
- Which form was tested: without DAC.
- The batch number, matching the vial label.
- An HPLC purity figure and an identity result.
Batch documents are on the COAs page.
Frequently asked questions
Is CJC-1295 without DAC the same as Mod GRF 1-29?
Yes. CJC-1295 without DAC and Modified GRF (1-29) are two names for the same 29-amino-acid GHRH analogue.
What does DAC stand for in CJC-1295?
DAC stands for drug affinity complex, a linker added to the peptide that is designed for albumin binding.
What is the CAS number for CJC-1295 without DAC?
The CAS number for CJC-1295 without DAC is 863288-34-0.
How many amino acids are in CJC-1295 without DAC?
Twenty-nine. It carries four substitutions relative to the native GRF (1-29) sequence.
What is in the CJC-1295 + Ipamorelin blend?
One premixed vial containing CJC-1295 (No DAC) 5mg and Ipamorelin 5mg, 10mg in total.
All Ascend Research products are sold strictly for laboratory research use only. They are not for human or animal use, and nothing in this article is medical advice.
The Ascend Research team